Cialis Black (Tadalafil) is a medication that is used to treat erectile dysfunction. It belongs to a group of drugs called phosphodiesterase type 5 inhibitors (PDE-5).
The mechanism of action of tadalafil is that it relaxes the smooth muscles in the penis and increases blood flow to it. As a result, a man gets an erection.
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Tadalafil was developed and patented in the USA by Eli Lilly and Company in 1998. The patent for the drug expired in 2011, after which other pharmaceutical companies began producing analogues of tadalafil.
Research on tadalafil has been conducted in various scientific centers in the United States. Here are some of them:
- A study conducted at the University of North Carolina at Chapel Hill showed that tadalafil is effective for the treatment of erectile dysfunction of various etiologies. The results of the study were published in The Journal of Urology.
- A study published in the Journal of Sexual Medicine showed that taking tadalafil in combination with sildenafil (viagra) may be effective in treating patients with erectile dysfunction that cannot be treated with tadalafil alone.
- The study, the results of which were published in The New England Journal of Medicine, demonstrated that tadalafil is safe and effective for the long-term treatment of erectile dysfunction in men over 65 years of age.
- A study presented at the annual meeting of the American Urological Association in 2009 showed that a combination of tadalafil and penile prosthesis therapy may be effective in treating some forms of erectile deformity.
It is important to note that before taking tadalafil, it is necessary to consult a doctor. Self-medication can lead to serious side effects.
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